BDBM683367 (S)-2-((7-amino-2-(furan-2-yl)- [1,2,4]triazolo[1,5-a][1,3,5]triazin-5- yl)amino)-1-(4-(2,4- difluorobenzyl)piperazin-1-yl)-2- phenylethan-1-one::US20240217978, Example 14

SMILES Nc1nc(N[C@H](C(=O)N2CCN(Cc3ccc(F)cc3F)CC2)c2ccccc2)nc2nc(nn12)-c1ccco1

InChI Key InChIKey=XESOIDXTFHHZBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683367   

TargetAdenosine receptor A2a(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM683367(US20240217978, Example 14 | (S)-2-((7-amino-2-(fur...)
Affinity DataIC50: 0.368nMAssay Description:A radioligand binding test was conducted by using [3H]-NECA (5′-N-[adenine-2,8-3H]-ethylcarboxamidoadenosine) and an adenosine A2a membrane. As...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent