BDBM683468 Ethyl 4-(4-((7-amino-2-(furan-2-yl)- [1,2,4]triazolo[1,5-a][1,3,5]triazin-5- yl)-L-prolyl)piperazin-1-yl)benzoate::US20240217978, Example 123

SMILES CCOC(=O)c1ccc(cc1)N1CCN(CC1)C(=O)[C@@H]1CCCN1c1nc(N)n2nc(nc2n1)-c1ccco1

InChI Key InChIKey=GLWXCFHFZPRMAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683468   

TargetAdenosine receptor A2a(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM683468(US20240217978, Example 123 | Ethyl 4-(4-((7-amino-...)
Affinity DataIC50: 0.5nMAssay Description:A radioligand binding test was conducted by using [3H]-NECA (5′-N-[adenine-2,8-3H]-ethylcarboxamidoadenosine) and an adenosine A2a membrane. As...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
US Patent