BDBM683511 (2S)-2-((7-amino-2-(furan-2-yl)- [1,2,4]triazolo[1,5-a][1,3,5]triazin-5- yl)amino)-1-(4-(2,4- difluorophenyl)piperazin-1-yl)-3- methylpentan-1-one::US20240217978, Example 166

SMILES CCC(C)[C@H](Nc1nc(N)n2nc(nc2n1)-c1ccco1)C(=O)N1CCN(CC1)c1ccc(F)cc1F

InChI Key InChIKey=SLLFLWOIFHLPQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683511   

TargetAdenosine receptor A2a(Human)
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM683511(US20240217978, Example 166 | (2S)-2-((7-amino-2-(f...)
Affinity DataIC50: 0.0800nMAssay Description:A radioligand binding test was conducted by using [3H]-NECA (5′-N-[adenine-2,8-3H]-ethylcarboxamidoadenosine) and an adenosine A2a membrane. As...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent