BDBM686210 US20240245673, Example 362

SMILES CN(C)C(=O)CCn1cc(cn1)-c1cc(c2ccccc2n1)C1(CC1)NC(=O)c1ccc(COCc2cscn2)cc1C

InChI Key InChIKey=DNUYHCCLSSXGJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686210   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM686210(US20240245673, Example 362)
Affinity DataIC50: 1nMAssay Description:The potency of compounds against the SARS-CoV-2 Papain like protease (PLpro) was measured using a synthetic profluorogenic substrate Z-RLRGG-AMC. Com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent