BDBM686498 Rac-3-(1-((cis)-2-((2-(2,4-dioxo-3- azabicyclo[3.1.1]heptan-1-yl)-1- oxoisoindolin-5- yl)oxy)cyclohexyl)azetidin-3- yl)benzonitrile::US20240246935, Example 77

SMILES N#Cc1cccc(C2CN([C@H]3CCCC[C@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)c1

InChI Key InChIKey=VDGISIMRXHLHBN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686498   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686498BDBM686498(US20240246935, Example 77 | Rac-3-(1-((cis)-2-((2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent