BDBM686515 Rac-2-(1-((cis)-2-((2-(2,4-dioxo-3- azabicyclo[3.1.1]heptan-1-yl)-1- oxoisoindolin-5- yl)oxy)cyclohexyl)azetidin-3- yl)benzonitrile::US20240246935, Example 94

SMILES N#Cc1ccccc1C1CN([C@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C24CC(C2)C(=O)NC4=O)C3=O)C1

InChI Key InChIKey=SLXLIDSVARTODS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686515   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686515BDBM686515(US20240246935, Example 94 | Rac-2-(1-((cis)-2-((2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent