BDBM686517 Rac-3-(5-(((trans)-2-(3-hydroxy-3- phenylazetidin-1- yl)cyclohexyl)oxy)-1- oxoisoindolin-2-yl)piperidine-2,6- dione::US20240246935, Example 96

SMILES CC1(CN(C1)[C@H]1CCCC[C@@H]1Oc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O)c1ccccc1

InChI Key InChIKey=NECVJOWEYYAELX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686517   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686517BDBM686517(US20240246935, Example 96 | Rac-3-(5-(((trans)-2-(...)
Affinity DataEC50:  42nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent