BDBM686519 4-(1-(2-((2-(2,6-dioxopiperidin-3- yl)-1-oxoisoindolin-5- yl)oxy)cyclopentyl)azetidin-3- yl)benzonitrile::US20240246935, Example 98

SMILES O=C1N(Cc2cc(OC3CCCC3N3CC(C3)c3ccc(cc3)C#N)ccc12)C1CCC(=O)NC1=O

InChI Key InChIKey=WZHDLMDPIYZYGB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686519   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686519BDBM686519(US20240246935, Example 98 | 4-(1-(2-((2-(2,6-dioxo...)
Affinity DataEC50:  32nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent