BDBM686526 1-(1-oxo-5-(((1S,2S)-2-(3- phenylazetidin-1- yl)cyclopentyl)oxy)isoindolin-2- yl)-3-azabicyclo[3.1.1]heptane- 2,4-dione::US20240246935, Example 105

SMILES O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCC[C@@H]5N5CC(c6ccccc6)C5)ccc4C3=O)CC1C2

InChI Key InChIKey=YDPHRJUTDBUMTN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686526   

TargetProtein cereblon(Human)
Plexium, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 686526BDBM686526(US20240246935, Example 105 | 1-(1-oxo-5-(((1S,2S)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent