BDBM689198 N-(Trans-3-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclobutyl)-2-methyloxazole-4-carboxamide::US12617759, Example 26A::US20240254109, Example 18A
SMILES Cc1nc(C(=O)N[C@H]2C[C@H](CCN3CCN(c4cccc(Cl)c4Cl)CC3)C2)co1
InChI Key InChIKey=GWCQURQWDAMSTD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 689198
Affinity DataIC50: 0.420nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Dopamine D3 Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 10 mm MgCl2; washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solut...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37nMAssay Description:5-HT2A Receptor: Experimental buffer: 50 mM Tris-HCl pH 7.4, 4 mM CaCl2); washing liquor: 50 mM Tris-HCl pH 7.4, stored at 4° C.; 0.5% PEI solution: ...More data for this Ligand-Target Pair