BDBM689288 Synthesis of 1-Methyl-6-(1H-pyrazol-4-yl)-N-{[2-(trifluoromethyl)phenyl]methyl}pyrrolo[2,3-b]pyridine-2-carboxamide ::US20240254124, Compound 14

SMILES CC[C@H]1CC(=O)N[C@@H]1COc3cccc4cc(C(N)=O)c2nccn2c34

InChI Key InChIKey=MGDUDQCPMMRYHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689288   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM689288(US12286428, Example 3)
Affinity DataIC50: 1.70nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substrates (fluor...More data for this Ligand-Target Pair
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Date in BDB:
11/20/2024
Entry Details
US Patent