BDBM689300 6-amino-2-((1R,3R)-1-amino- 3-methyl-8- azaspiro[4.5]decan-8-yl)-3- methyl-5-((3- (trifluoromethyl)pyridin-4- yl)thio)pyrimidin-4(3H)-one::US12053470, Compound 28

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc(N)c(Sc2ccncc2C(F)(F)F)c(=O)n1C

InChI Key InChIKey=GHNNUZAENHZAOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 689300   

LigandPNGBDBM689300(US12053470, Compound 28 | 6-amino-2-((1R,3R)-1-ami...)
Affinity DataIC50: 18nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent