BDBM689590 US20240261292, Compound A1

SMILES CCN(C(C)C)C(=O)c1cc(F)ccc1Oc1nncnc1N1CCC2(CN(C2)[C@H](CCCN(C)CCOC)C(C)C)C1

InChI Key InChIKey=PDUGAXSIWNMIBQ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 689590   

TargetMenin(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 0.180nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200�� test compound in DMSO and 4 uL 2�� terbium chelate-labeled menin (vide infra f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetHistone-lysine N-methyltransferase 2A(Human)
Janssen Pharmaceutica NV

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetMenin(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent
PDB3D3D Structure (crystal)
TargetMenin(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent
PDB3D3D Structure (crystal)
TargetMenin(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 689590BDBM689590(US20240261292, Compound A1 | US12473295, Compound ...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent
PDB3D3D Structure (crystal)