BDBM692492 US20240270735, Compound A5

SMILES CCCCc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1

InChI Key InChIKey=LGLMBMOHTQLXBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 692492   

TargetCyclin-dependent kinase 19(Human)
Chan Zuckerberg Biohub

US Patent
LigandPNGBDBM692492(US20240270735, Compound A5)
Affinity DataIC50: 7nMAssay Description:The CDK19/CDK8 IC50 values were measured to evaluate activity and to determine CDK19/CDK8 selectivity. The IC50 values of the disclosed compounds was...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 8(Human)
Chan Zuckerberg Biohub

US Patent
LigandPNGBDBM692492(US20240270735, Compound A5)
Affinity DataIC50: 94nMAssay Description:The CDK19/CDK8 IC50 values were measured to evaluate activity and to determine CDK19/CDK8 selectivity. The IC50 values of the disclosed compounds was...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent