BDBM693396 N-(2,3-difluoro-4-((3-(2-(((3S,5S)-5- fluoropiperidin-3-yl)amino)pyrimidin-4- yl)pyridin-2-yl)oxy)-5-methylphenyl)-1- phenylethane-1-sulfonamide::US12071425, Compound 314

SMILES Cc2cc(NS(=O)(=O)[C@H](C)c1ccccc1)c(F)c(F)c2Oc3ncccc3c5ccnc(N[C@@H]4CNC[C@@H](F)C4)n5

InChI Key InChIKey=KDCTVYIZVJRXTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693396   

LigandChemical structure of BindingDB Monomer ID 693396BDBM693396(N-(2,3-difluoro-4-((3-(2-(((3S,5S)-5- fluoropiperi...)
Affinity DataIC50: 0.240nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
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Date in BDB:
12/6/2024
Entry Details
US Patent