BDBM693400 1-phenyl-N-(2,3,6-trifluoro-4-((3-(2-((5- methoxypiperidin-3-yl)amino)pyrimidin- 4-yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide::US12071425, Compound 318

SMILES CO[C@@H]5CNC[C@H](Nc4nccc(c1cccnc1Oc3cc(F)c(NS(=O)(=O)Cc2ccccc2)c(F)c3F)n4)C5

InChI Key InChIKey=BOMCYRFRWPDJDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693400   

LigandChemical structure of BindingDB Monomer ID 693400BDBM693400(1-phenyl-N-(2,3,6-trifluoro-4-((3-(2-((5- methoxyp...)
Affinity DataIC50: 0.300nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
US Patent