BDBM696719 N-(5-((3R,4S)-3-(2- hydroxypropan-2-yl)-4- methoxypyrrolidin-1-yl)-2- (trifluoromethyl)pyridin-3-yl)-6- (1-(2,2,2-trifluoroethyl)-1H- pyrazol-4-yl)picolinamide::US20240308980, Ex-2.1

SMILES CO[C@@H]1CN(C[C@H]1C(C)(C)O)c1cnc(c(NC(=O)c2cccc(n2)-c2cnn(CC(F)(F)F)c2)c1)C(F)(F)F

InChI Key InChIKey=WAQSUDWZSDUZHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696719   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696719(N-(5-((3R,4S)-3-(2- hydroxypropan-2-yl)-4- methoxy...)
Affinity DataIC50: 1.62E+3nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent