BDBM696748 6-(1-methyl-1H-pyrazol-4-yl)-N- (2-(4-(oxetan-3-yl)piperidin-1- yl)-5-(trifluoromethyl)pyridin-4- yl)picolinamide::US20240308980, Ex-4.19

SMILES Cn1cc(cn1)-c1cccc(n1)C(=O)Nc1cc(ncc1C(F)(F)F)N1CCC(CC1)C1COC1

InChI Key InChIKey=GICLWONWLYUGDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696748   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696748(6-(1-methyl-1H-pyrazol-4-yl)-N- (2-(4-(oxetan-3-yl...)
Affinity DataIC50: 2.13E+3nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent