BDBM696797 (S)-6-(1-((1- cyanocyclopropyl)methyl)-1H- pyrazol-4-yl)-N-(6-(3-methyl-4- (oxetan-3-yl)piperazin-1- yl)pyrimidin-4-yl)picolinamide::US20240308980, Ex-7.9

SMILES C[C@H]1CN(CCN1C1COC1)c1cc(NC(=O)c2cccc(n2)-c2cnn(CC3(CC3)C#N)c2)ncn1

InChI Key InChIKey=NMQHOXPDLLBHCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696797   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696797((S)-6-(1-((1- cyanocyclopropyl)methyl)-1H- pyrazol...)
Affinity DataIC50: 650nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent