BDBM696802 N-[3-cyclopropyl-6-[(3R)-3-(1- ethyl)pyrrolidin-1-yl]pyridazin- hydroxy-1-methyl- 4-yl]-6-(1-methylpyrazol-4- yl)pyridine-2-carboxamide::US20240308980, Ex-10.2

SMILES Cn1cc(cn1)-c1cccc(n1)C(=O)Nc1cc(nnc1C1CC1)N1CC[C@@H](C1)C(C)(C)O

InChI Key InChIKey=LIHLZFQUUDQYPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696802   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM696802(N-[3-cyclopropyl-6-[(3R)-3-(1- ethyl)pyrrolidin-1-...)
Affinity DataIC50: 774nMAssay Description:Compound potency against LRRK2 kinase activity was determined using LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA) using a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent