BDBM697147 US20240309018, Compound WX001

SMILES Cc1cccc(CN2C(=O)c3nc(sc3C22COC2)-c2nc(Nc3ccnn3C)ncc2C)n1

InChI Key InChIKey=XDQJPNLCRUUTCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 697147   

TargetMitogen-activated protein kinase 1(Human)
D3 Bio (Wuxi)

US Patent
LigandPNGBDBM697147(US20240309018, Compound WX001)
Affinity DataIC50: 0.540nMAssay Description:1. Purpose of the Assay:The ability of the compound to inhibit ERK1 and ERK2 kinase activity was measured.2. Assay Buffer:20 mM Hepes (pH 7.5), 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase 3(Human)
D3 Bio (Wuxi)

US Patent
LigandPNGBDBM697147(US20240309018, Compound WX001)
Affinity DataIC50: 1.40nMAssay Description:1. Purpose of the Assay:The ability of the compound to inhibit ERK1 and ERK2 kinase activity was measured.2. Assay Buffer:20 mM Hepes (pH 7.5), 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
US Patent