BDBM698040 US20240317714, Example A34

SMILES CN1CCC(CC1)n1cc(Oc2nc(cnc2N)-c2cc(C)c(C(=O)NCCN3CC[C@@H](F)C3)c(C)c2)cn1

InChI Key InChIKey=IGTYEXMPMYGLTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 698040   

LigandChemical structure of BindingDB Monomer ID 698040BDBM698040(US20240317714, Example A34 | US20250236610, Exampl...)
Affinity DataIC50: 65nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aa1-346, Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 698040BDBM698040(US20240317714, Example A34 | US20250236610, Exampl...)
Affinity DataIC50: 65nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aal-346. Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 698040BDBM698040(US20240317714, Example A34 | US20250236610, Exampl...)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetLymphocyte cytosolic protein 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 698040BDBM698040(US20240317714, Example A34 | US20250236610, Exampl...)
Affinity DataIC50: 155nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed