BDBM69805 3-[(2-pyridin-4-yl-4-quinazolinyl)amino]benzoic acid methyl ester::3-[[2-(4-pyridyl)quinazolin-4-yl]amino]benzoic acid methyl ester::MLS001163930::SMR000539298::cid_1418188::methyl 3-[(2-pyridin-4-ylquinazolin-4-yl)amino]benzoate

SMILES COC(=O)c1cccc(Nc2nc(nc3ccccc23)-c2ccncc2)c1

InChI Key InChIKey=ASQQSYXQQGXDBY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 69805   

LigandPNGBDBM69805(MLS001163930 | SMR000539298 | cid_1418188 | methyl...)
Affinity DataIC50: 405nMAssay Description:Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM69805(MLS001163930 | SMR000539298 | cid_1418188 | methyl...)
Affinity DataIC50: 6.37E+3nMAssay Description:Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels preincubated for 30 mins followed by calcein AM addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69805(MLS001163930 | SMR000539298 | cid_1418188 | methyl...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay