BDBM698790 2-((5-(6-oxa-1- azaspiro[3.3]heptane-1- carbonyl)pyrimidin-2- yl)amino)-6-chloro-2,3- dihydro-1H-indene-4- carbonitrile::US12600712, Example 4

SMILES N#Cc1cc(Cl)cc2c1CC(Nc1ncc(C(=O)N3CCC34COC4)cn1)C2

InChI Key InChIKey=IEGMVFCMBVSNLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698790   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698790BDBM698790(2-((5-(6-oxa-1- azaspiro[3.3]heptane-1- carbonyl)p...)
Affinity DataIC50: 20.8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent