BDBM698796 (2-((6-chloro-4-fluoro- 2,3-dihydro-1H-inden- 2-yl)amino)pyrimidin- 5-yl)(6-oxa-1- azaspiro[3.3]heplan-l - yl)melhanone::US12600712, Example 8

SMILES O=C(c1cnc(NC2Cc3cc(Cl)cc(F)c3C2)nc1)N1CCC12COC2

InChI Key InChIKey=JISUDPISOBNPCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698796   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698796BDBM698796((2-((6-chloro-4-fluoro- 2,3-dihydro-1H-inden- 2-yl...)
Affinity DataIC50: 111nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent