BDBM698798 (2-((6-chloro-4- (trifluoromethyl)-2,3- dihydro-1 H-inden-2- yl)amino)pyrimidin-5- yl)(6-oxa-1- azaspiro[3.3]heptan-1- yl)melhanone::US12600712, Example 10

SMILES O=C(c1cnc(NC2Cc3cc(Cl)cc(C(F)(F)F)c3C2)nc1)N1CCC12COC2

InChI Key InChIKey=PAEZZELSRNLXLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698798   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 698798BDBM698798((2-((6-chloro-4- (trifluoromethyl)-2,3- dihydro-1 ...)
Affinity DataIC50: 184nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent