BDBM698812 (2-((1- ((dimethylamino)methyl)cyclopropyl) methoxy)-4-(1,4-thiazepan-4-yl)-5,7- dihydro-6H-pyrrolo[3,4-d]pyrimidin- 6-yl)(3-hydroxy-8-iodonaphthalen-1- yl)methanone::US20240317759, Example 22

SMILES CC(C)Oc1nc(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)c(C(N)=O)nc1-c1ccccc1

InChI Key InChIKey=DJEKDMDLTUOFOX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698812   

TargetEpidermal growth factor receptor(Human)
Wigen Biomedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698812BDBM698812(US12600714, Compound 14)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent