BDBM698813 (2-((1- ((dimethylamino)methyl)cyclopropyl) methoxy)-4-(3-methylazepan-1-yl)- 5,7-dihydro-6H-pyrrolo[3,4-d] pyrimidin-6-yl)(3-hydroxy-8- iodonaphthalen-1-yl)methanone::US20240317759, Example 23

SMILES CN1CCN(C2CCN(c3ccc(Nc4nc(NCC(C)(C)O)c(-c5ccccc5)nc4C(N)=O)cc3)CC2)CC1

InChI Key InChIKey=PHTCNFSCDCVMIB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698813   

TargetEpidermal growth factor receptor(Human)
Wigen Biomedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698813BDBM698813(US12600714, Compound 21)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent