BDBM698817 1-(2-((1- ((dimethylamino)methyl)cyclopropyl) methoxy)-6-(3-hydroxy-8-iodo-1- naphthoyl)-6,7-dihydro-5H-pyrrolo [3,4-d]pyrimidin-4-yl)azepane- 4-carbonitrile::US20240317759, Example 27

SMILES CN1CCN(C2CCN(c3ccc(Nc4nc(NC5CCOCC5)c(-c5cn[nH]c5)nc4C(N)=O)cc3)CC2)CC1

InChI Key InChIKey=FVNHHOXERXKJGA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698817   

TargetEpidermal growth factor receptor(Human)
Wigen Biomedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698817BDBM698817(US12600714, Compound 57)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent