BDBM698879 (2-((1-((4-fluoropiperidin-1- yl)methyl)cyclopropyl)methoxy)-4-(2- methylazepan-1-yl)-5,7-dihydro-6H- pyrrolo[3,4-d]pyrimidin-6-yl)(3-hydroxy-8- iodonaphthalen-1-yl)methanone::US20240317759, Example 88

SMILES C=CC(=O)N(C)CC#Cc1c(N)ncnc1-c1cc(F)cc(-n2ccc3cc(C4CC4)cc(F)c3c2=O)c1C

InChI Key InChIKey=HEMKHCJEIGYZEL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698879   

TargetTyrosine-protein kinase BTK(Human)
Hanmi Pharm. Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698879BDBM698879(US20260103453, Example 8)
Affinity DataIC50: 3.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent