BDBM698880 1-((1-(((6-(3-hydroxy-8-iodo-1-naphthoyl)-4- (2-methylazepan-1-yl)-6,7-dihydro-5H- pyrrolo[3,4-d]pyrimidin-2- yl)oxy)methyl)cyclopropyl)methyl)piperidine- 4-carbonitrile::US20240317759, Example 89

SMILES C=CC(=O)NCC#Cc1c(N)ncnc1-c1cc(F)cc(-n2ccc3cc(C4CC4)cc(F)c3c2=O)c1

InChI Key InChIKey=YBHKPBUPBBWZOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698880   

TargetTyrosine-protein kinase BTK(Human)
Hanmi Pharm. Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698880BDBM698880(US20260103453, Example 9)
Affinity DataIC50: 34nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent