BDBM698889 2-(1-((1-(((4-((R)-3-hydroxy-3-methylpiperidin- 1-yl)-6-(3-hydroxy-8-iodo-1-naphthoyl)-6,7- dihydro-5H-pyrrolo[3,4-d]pyrimidin-2- yl)oxy)methyl)cyclopropyl)methyl)piperidin-3- yl)acetonitrile::US20240317759, Example 98

SMILES C=CC(=O)N1CCC[C@H]1C#Cc1c(N)ncnc1-c1cc(F)cc(-n2ccc3cc(C(C)C)cc(F)c3c2=O)c1C

InChI Key InChIKey=RAWICLSHWKKTKG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698889   

TargetTyrosine-protein kinase BTK(Human)
Hanmi Pharm. Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 698889BDBM698889(US20260103453, Example 18)
Affinity DataIC50: 9.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent