BDBM699282 2-[(2-{2'-chloro-5'-methoxy-6-methyl- [4,4'-bipyridine]-3-amido}-1,3- benzothiazol-5-yl)oxy]ethyl acetate::US20240327430, Example 123

SMILES COc1cnc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2cc(OCCOC(C)=O)ccc2s1

InChI Key InChIKey=LFUZFSIFQOBMET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 699282   

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM699282(2-[(2-{2'-chloro-5'-methoxy-6-methyl- [4,4'-bipyri...)
Affinity DataIC50: 100nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Polθ protein (P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM699282(2-[(2-{2'-chloro-5'-methoxy-6-methyl- [4,4'-bipyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Pol&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent