BDBM699517 US12110286, Example 5

SMILES COC(=O)C(C)CCn1c2cc(Nc3cc(nc(Cl)c3C#N)-c3nc(C)no3)ccc2n(C)c1=O

InChI Key InChIKey=VSQLRDIEXXEMOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 699517   

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 699517BDBM699517(US12110286, Example 5)
Affinity DataIC50: 646nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 699517BDBM699517(US12110286, Example 5)
Affinity DataIC50: 1.02E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent