BDBM699610 US12110286, Example 25h

SMILES Cn1c2ccc(Nc3ccnc(Cl)c3C#N)cc2n(C[C@@H]2C[C@H](F)CN2CC(F)(F)F)c1=O

InChI Key InChIKey=BPMJWCGFBNUBIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699610   

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 699610BDBM699610(US12110286, Example 25h)
Affinity DataIC50: 2.82E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent