BDBM699629 US12110286, Example 31b

SMILES Cn1c2ccc(Nc3cc(nc4c(cnn34)C#N)N3CCC[C@H]3CO)cc2n(CCC(C)(C)O)c1=O

InChI Key InChIKey=HPAXMRQJWOKPFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699629   

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 699629BDBM699629(US12110286, Example 31b)
Affinity DataIC50: 1.86E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent