BDBM703854 4-methyl-7-phenyl-1,5-naphthyridin-2-amine LCMS [M + 1]: 236.3. 1H NMR (400 MHz, MeOD) $#948; = 8.79 (d, J = 2.4 Hz, 1H), 8.03 (d, J = 2.4 Hz, 1H), 7.81-7.68 (m, 2H), 7.56-7.50 (m, 2H), 7.47- 7.41 (m, 1H), 6.92 (d, J = 0.8 Hz, 1H), 2.65 (d, J = 0.8 Hz, 3H).::US20240368153, Example 1-1

SMILES Cc1cc(N)nc2cc(-c3ccccc3)cnc12

InChI Key InChIKey=CDSMVLOAJAFUKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703854   

LigandChemical structure of BindingDB Monomer ID 703854BDBM703854(4-methyl-7-phenyl-1,5-naphthyridin-2-amine LCMS [M...)
Affinity DataIC50: 1.72E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2025
Entry Details
US Patent