BDBM703871 4-methyl-7-(pyridin-2-yl)-1,5-naphthyridin-2- amine LCMS [M + 1]: 237.2. H NMR (400 MHz, MeOD) $#948; = 9.13 (d, J = 2.0 Hz, 1H), 8.73-8.68 (m, 1H), 8.36 (d, J = 2.0 Hz, 1H), 8.03-7.92 (m, 2H), 7.43 (m, 1H), 6.95 (d, J = 1.2 Hz, 1H), 2.65 (d, J = 1.2 Hz, 3H).::US20240368153, Example 1-2

SMILES Cc1cc(N)nc2cc(-c3ccccn3)cnc12

InChI Key InChIKey=XGARVOSZCBNAAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703871   

LigandChemical structure of BindingDB Monomer ID 703871BDBM703871(4-methyl-7-(pyridin-2-yl)-1,5-naphthyridin-2- amin...)
Affinity DataIC50: 8.20E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent