BDBM703889 4-methyl-7-(1-methyl-1H-pyrazol-4-yl)-1,5- naphthyridin-2-amine LCMS [M + 1]: 240.3. 1H NMR (400 MHz, MeOD) $#948; = 8.73 (d, J = 2.0 Hz, 1H), 8.16 (s, 1H), 7.97 (d, J = 0.8 Hz, 1H), 7.91 (d. J = 2.0 Hz, 1H), 6.85 (d, J = 1.2 Hz, 1H), 3.97 (s, 3H), 2.61 (d, J = 1.2 Hz, 3H).::US20240368153, Example 1-7

SMILES Cc1cc(N)nc2cc(-c3cnn(C)c3)cnc12

InChI Key InChIKey=PWYQWZFPCNYPRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703889   

LigandChemical structure of BindingDB Monomer ID 703889BDBM703889(4-methyl-7-(1-methyl-1H-pyrazol-4-yl)-1,5- naphthy...)
Affinity DataIC50: 7.92E+3nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent