BDBM703892 4-methyl-7-(thiazol-4-ylmethyl)-1,5-naphthyridin- 2-amine. LCMS [M + 1]: 257.3. 1H NMR (400 MHz, MeOD) $#948; = 8.97 (d, J = 2.0 Hz, 1H), 8.47 (d, J = 2.0 Hz, 1H), 7.71-7.65 (m, 1H), 7.40-7.34 (m, 1H), 6.86 (d, J = 0.8 Hz, 1H), 4.33 (s, 2H), 2.60 (d, J = 0.8 Hz, 3H).::US20240368153, Example 2-10

SMILES Cc1cc(N)nc2cc(Cc3cscn3)cnc12

InChI Key InChIKey=IAGLJYUONMXPAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703892   

LigandChemical structure of BindingDB Monomer ID 703892BDBM703892(4-methyl-7-(thiazol-4-ylmethyl)-1,5-naphthyridin- ...)
Affinity DataIC50: 2.14E+3nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent