BDBM703896 4-methyl-7-(2-methylbenzyl)-1,5-naphtbyridin-2- amine LCMS [M + 1]: 264.3. 1H NMR (400 MHz, MeOD-d4) $#948; = 8.42 (d, J = 2.0 Hz, 1H), 7.54- 7.47 (m, 1H), 7.26-7.16 (m, 4H), 6.88 (d, J = 0.9 Hz, 1H), 4.19 (s, 2H), 2.62 (d, J = 0.9 Hz, 3H), 2.26 (s, 3H).::US20240368153, Example 2-5

SMILES Cc1ccccc1Cc1cnc2c(C)cc(N)nc2c1

InChI Key InChIKey=PHROCHIKWQWUBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703896   

LigandChemical structure of BindingDB Monomer ID 703896BDBM703896(4-methyl-7-(2-methylbenzyl)-1,5-naphtbyridin-2- am...)
Affinity DataIC50: 8.83E+3nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent