BDBM703905 4-methyl-7-(2-methylphenoxy)-1,5-naphtbyridin- 2-amine. LCMS [M + 1]: 266.2. 1H NMR (400 MHz, CDCl3) $#948; = 8.58 (d, J = 2.8 Hz, 1H), 7.29 (d, J = 7.2 Hz, 1H), 7.26-7.19 (m, 1H), 7.18-7.12 (m, 1H), 7.07- 7.02 (m, 2H), 6.67 (d, J = 0.8 Hz, 1H), 4.69 (br s, 2H), 2.69 (d, J = 0.8 Hz, 3H), 2.23 (s, 3H).::US20240368153, Example 3-5

SMILES Cc1ccccc1Oc1cnc2c(C)cc(N)nc2c1

InChI Key InChIKey=RPNRDQFDDYYRTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703905   

LigandChemical structure of BindingDB Monomer ID 703905BDBM703905(4-methyl-7-(2-methylphenoxy)-1,5-naphtbyridin- 2-a...)
Affinity DataIC50: 3.96E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent