BDBM703911 4-methyl-6-(3-pyridyl)-1,5-naphthyridin-2-amine. LCMS [M + 1] = 237.3. 1H NMR (400 MHz, MeOD) $#948; = 9.34 (d, J = 1.6 Hz, 1H), 8.62-8.58 (dd, J = 2.0 Hz, J = 8.0 Hz, 1H), 8.56 (dd, J = 1.6, 4.8 Hz, 1H), 8.10 (d, J = 8.8 Hz, 1H), 7.93 (d, J = 8.8 Hz, 1H), 7.56 (dd, J = 4.8, 7.6 Hz, 1H), 6.96 (d, J = 0.8 Hz, 1H), 2.72 (d, J = 0.8 Hz, 3H).::US20240368153, Example 4-3

SMILES Cc1cc(N)nc2ccc(-c3cccnc3)nc12

InChI Key InChIKey=WGSSYKREOPIKHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703911   

LigandChemical structure of BindingDB Monomer ID 703911BDBM703911(4-methyl-6-(3-pyridyl)-1,5-naphthyridin-2-amine. L...)
Affinity DataIC50: 2.39E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent