BDBM703916 6-(4-fluorophenyl)-4-methyl-1,5-naphthyridin-2- amine. LCMS [M + 1] = 254.2. 1H NMR (400 MHz, MeOD) $#948; = 8.20 (br dd, J = 6.0, 8.0 Hz, 2H), 8.00 (br d, J = 8.8 Hz, 1H), 7.87 (br d, J = 8.8 Hz, 1H), 7.20 (br t, J = 8.8 Hz, 2H), 6.93 (s, 1H), 2.71 (s, 3H).::US20240368153, Example 4-9

SMILES Cc1cc(N)nc2ccc(-c3ccc(F)cc3)nc12

InChI Key InChIKey=FKKCRKQBRSYTDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703916   

LigandChemical structure of BindingDB Monomer ID 703916BDBM703916(6-(4-fluorophenyl)-4-methyl-1,5-naphthyridin-2- am...)
Affinity DataIC50: 1.40E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent