BDBM703959 US20240368153, Example 15-6

SMILES Cc1cc2[nH]c(CNC(=O)c3ccccc3)c(C#N)c2nc1N

InChI Key InChIKey=QUVGHZVWWAPAJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 703959   

LigandChemical structure of BindingDB Monomer ID 703959BDBM703959(US20240368153, Example 15-6)
Affinity DataIC50: 2.64E+3nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 703959BDBM703959(US20240368153, Example 15-6)
Affinity DataIC50: 7.67E+4nMAssay Description:Table B1: The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 703959BDBM703959(US20240368153, Example 15-6)
Affinity DataIC50: 3.00E+5nMAssay Description:Table B1: The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent