BDBM704489 5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpholinoanilino)pyrazine-2-carboxamide::US20240374606, Example 42

SMILES Cn1cnc2c(-c3nc(C(N)=O)c(Nc4ccc(N5CCOCC5)cc4)nc3C(F)F)cncc21

InChI Key InChIKey=IFYFIPLCOHYJSO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 704489   

LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataIC50: 18nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetLymphocyte cytosolic protein 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataEC50:  72nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Lck(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataIC50: 1.26E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Lck(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 704489BDBM704489(5-(Difluoromethyl)-6-(3-methylimidazo[4,5-c]pyridi...)
Affinity DataIC50: 1.26E+3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent