BDBM704533 5-Cyclopropyl-3-[4-(1-hydroxy-1-methyl-ethyl)anilino]-6-(3-methylimidazo[4,5-c]pyridin-7-yl)pyrazine-2-carboxamide::US20240374606, Example 86

SMILES Cn1cnc2c(-c3nc(C(N)=O)c(Nc4ccc(C(C)(C)O)cc4)nc3C3CC3)cncc21

InChI Key InChIKey=SRTJPDZXTXFJPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 704533   

LigandPNGBDBM704533(5-Cyclopropyl-3-[4-(1-hydroxy-1-methyl-ethyl)anili...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandPNGBDBM704533(5-Cyclopropyl-3-[4-(1-hydroxy-1-methyl-ethyl)anili...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

US Patent
LigandPNGBDBM704533(5-Cyclopropyl-3-[4-(1-hydroxy-1-methyl-ethyl)anili...)
Affinity DataIC50: 91nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent