BDBM704599 5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrazine-2-carboxamide::US20240374606, Example 152

SMILES CN1CCN(Cc2ccc(Nc3nc(C4CC4)c(-c4cncc5c4ncn5C)nc3C(N)=O)cc2)CC1

InChI Key InChIKey=DPLYERNYYUCIOC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 704599   

LigandPNGBDBM704599(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandPNGBDBM704599(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

US Patent
LigandPNGBDBM704599(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 57nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent