BDBM704614 5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-[4-[(1-methyl-4-piperidyl)oxy]anilino]pyrazine-2-carboxamide::US20240374606, Example 167

SMILES CN1CCC(Oc2ccc(Nc3nc(C4CC4)c(-c4cncc5c4ncn5C)nc3C(N)=O)cc2)CC1

InChI Key InChIKey=JEBWWKDNSXECGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 704614   

LigandPNGBDBM704614(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandPNGBDBM704614(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

US Patent
LigandPNGBDBM704614(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 31nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent