BDBM70500 4-(7-(difluoro- methyl)-6-(1-methyl- 1H-pyrazol-4-yl)- 3,4-dihydroquinolin- 1(2H)-yl)-N-methyl- 1,3-dihydrofuran [3,4-c]pyridine-6- carboxamide::US12486251, Example 62

SMILES CNC(=O)c5cc1COCc1c(N4CCCc3cc(c2cnn(C)c2)c(C(F)F)cc34)n5

InChI Key InChIKey=LQPKMNRXBYTROA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 70500   

TargetCREB-binding protein(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 70500BDBM70500(4-(7-(difluoro- methyl)-6-(1-methyl- 1H-pyrazol-4-...)
Affinity DataIC50: 287nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent